oxicodone — oxicodone side effects, indications, usage

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Oxicodone is most commonly the misspelled word for oxycodone. However in today’s full guide article we will explain fully oxycodone side effects, precautions, uses, Interactions, overdose, and precautions about oxycodone.

What is oxicodone ? 

oxicodone ( oxycodone )  is a misspelled word for oxycodone and it is a medication that is being used to relieve moderate to severe pain. This drug belongs to the class of opioid analgesics. It acts in the central nervous system ( brain )  and they change how your body responds to pains and how your body feels. 

How to use oxicodone ( oxycodone ) 

It is always advisable to read the medication guide that is being provided by your UTV pharmacist before you begin or start taking this medication or each time you get a refill of your medication. If you have any questions or queries then do not hesitate to ask your doctor or Pharmacist. 

The oral form of oxycodone should be taken by mouth and as directed by your doctor. It can be taken with or without food, however, if you have nausea then it is best advised to take this medication with food. If you have the symptoms of nausea then you can always ask your doctor or pharmacist how to reduce or decrease nausea. One of the most commonly effective ways to reduce the symptoms of nausea is by lying down for 1 to 2 hours with as little head movement. 

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Grapefruits can increase the side effects of this medication while taking oxicodone ( oxycodone ). So grapefruit or drinking grapefruits should be avoided while taking this medication unless your doctor or Pharmacist asked you to do so safely. You may also ask your Pharmacist or Doctor for more details. If you are taking this liquid form of oxycodone, then always measure the dose of this drug carefully with a measuring device or spoon. Never use a household spoon as this may not give you the accurate or correct dose.  You may also ask your doctor or pharmacist if you are not sure how to measure the dose of this medication. 

The dosage of this medication is based on how you respond to treatment or your medical conditions. Always make sure you take the accurate dose as prescribed by your doctor and never increase your dose of oxycodone or take it more frequently, or take it for a longer time than prescribed. This medication is an opioid analgesic and it can be addictive so properly stop the medication as directed by your doctor. 

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What Are The Side Effects Of oxicodone ? 

Generally, all opioids are always so addicting, oxicodone is also known as oxycodone it has a huge risk to cause addiction and abuse, and this can eventually lead to overdose as well as death.  It can also cause some severe or even fatal problems in breathing. For the lower risk of all these effects, it is advisable to inform your doctor about it and your doctor should definitely let you take the smallest dose of oxycodone that works perfectly. It is always recommended to take opioids for a short period of time. 

oxicodone may cause different side effects such as ; 

i.  Stomach pain-: This type of pain usually occurs in the outer muscle wall or in the abdomen. 

ii. Drowsiness-: This side effect of oxycodone causes drowsiness which makes you feel lethargic and sleepy.   

iii. Mood changes-: oxycodone causes mood changes or also mood swings that actually refer to sudden or rapid changes in mood. 

iv. Headache-: The side effect of oxycodone is a headache and usually this headache type of painful sensation. And usually, this pain occurs in any part of the head which might actually range from dull to sharp pain. 

There are some side effects of this drug that can be so serious, however, if you ever have or experience any of these side effects we have listed above then we strongly recommend you to inform or call your doctor immediately. Most especially symptoms like changes in heartbeat, hallucinations ( seeing things that are not real or hearing voices that aren’t real )-, fast heartbeats, difficulty breathing, rash, seizures, swelling of the tongue, face, ankles, eyes, hands, throat, lips. 

Oxycodone is a prescription drug which means that it can only be prescribed by a healthcare professional who has solid knowledge of how to use opioids for the management of any chronic pain.  

This drug is advised to be swallowed whole, it should not chew-, break, crush or dissolve. Because when the drug is chewed, broken, or dissolved it can actually release all the drugs at once and this can increase the risk of oxycodone overdose. So it is always advised to use this drug at once. 

To reduce or lessen any chance of having trouble swallowing or choking it is advisable to use or take just 1 tablet at a time if eventually, your dose is more than 1. 

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Before placing oxicodone (oxycodone) in your mouth do not lick, wet, or even pre-soak it. It is important to take adequate water with every tablet.   

Before you start using this medication, it is very important for you to ask your doctor or pharmacist if you should actually stop or even change how you take or use other medications that are pain relievers or opioid analgesics. Some other pain relievers are-; Non- steroidal anti-inflammatory drugs ( NSAIDs ) such as ibuprofen, diclofenac, etc. Make sure you ask your pharmacist or doctor if oc80 can be safely used with other drugs. 

Opioid acts in the central nervous system (CNS) which means they act in the brain so when oxycodone is being stopped suddenly especially when it has been used for a very long period of time such patient that uses the drug may experience “ Withdrawal symptoms ” one of the best and the most effective ways to reduce or prevent the withdrawal syndrome is that your doctor should reduce the dose slowly. 

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In case you don’t know what withdrawal symptoms are, they include-; anxiety, diarrhea, muscle aches, nausea, restlessness, trouble sleeping, running nose, thoughts of suicide, sudden changes in behavior, and watering eyes. 

When drugs like this are being used for a very long period of time they do not work properly anymore. So if you experience this do not hesitate to talk to your doctor when all your medications do not really work well when it stops working. 

You have to understand that this drug can be very helpful and also It can be so addicting. It is proper and ideal to use this drug as prescribed by your doctor or Pharmacist. If the pain keeps persisting or if it gets worse then inform your doctor immediately. 

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oxicodone (oxycodone)

Interaction of drugs can actually change how your medications work or it can increase your risk for very serious side effects. There are some products that can interact with oxycodone which are mixed opioid agonists or antagonists e.g butorphanol and pentazocine. 

Increased side effects of drowsiness may occur when this medication is being taken with some other medications that can also cause drowsiness. You need to inform your doctor or pharmacist if you take other opioids alongside oxicodone (oxycodone). There are some cough suppressants that contain opioids such as ; 

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i. Codeine: Codeine is a prodrug of morphine and it is generally known as an opiate. It is usually used to suppress coughing as well as diarrhea. This drug is found in the sap of opium poppy. Codeine can also be used to treat any mild to moderate pains. 

ii. Pholcodine: Pholcodine is generally is also known as morpholinyl ethyl morphine. It is a drug that is referred to as an opioid cough suppressant ( antitussive ). But this drug has almost no analgesic effects and it helps to suppress any unproductive coughs.  It also contains mild sedative effects. 

iii. Hydrocodone: It is also an opioid that is used for the treatment of coughs. And also when you take alcohol, and drugs that are used to induce sleep such as ; 

iv. Zolpidem: Zolpidem is a short-term treatment of sleep problems. It is being sold under the brand name Ambien. 

v. lorazepam: oxycodone can also interact with some muscle relaxant drugs such as; cyclobenzaprine and carisoprodol. It also interacts with antihistamines. Antihistamines are types of drugs that are being used to treat allergic reactions such as sneezing etc. And one of the side effects of antihistamines is that they cause drowsiness.

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It is very important for people who use opioids to always check the labels of all their drugs. Because there are some drugs like cough suppressants they may cause drowsiness

Some medications such as azole antifungal such as ketoconazole could actually affect the removal of oxycodone from the body. And this may actually affect the way the drug works. Antibiotics such as erythromycin which is under macrolide class could also affect how the drug works.


If you are allergic to oxycodone or other benzodiazepines which include lorazepam, diazepam or any other allergies then make sure you inform your doctor immediately. If you also have any medical history of breathing problems, kidney disease, or liver disease then inform your doctor immediately. 

This medication may cause drowsiness, so when you take this medication with some other medications that can cause drowsiness then the side effects may be increased.

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